Katharina Maisel (UMD Fischell Department of Bioengineering): Nanoparticles to cross and probe biological barriers to immunotherapy

Speaker: Katharina Maisel, UMD Fischell Department of Bioengineering

Host: Arpita Upadhyaya

Abstract: The Mucosal Associated Immune System Engineering and Lymphatics (MAISEL) Lab’s research integrates nanotechnology, materials science, and tissue engineering with physiology, medicine, and immunology to probe lymphatics and extracellular barriers via novel ex vivo and in vitro models and nanoparticles. We are particularly focused on studying mucosal barriers to the therapeutic path from the mucosal lumen to the downstream lymph nodes and integrating the newly created knowledge to design immune modulatory therapeutic interventions. We have made significant progress in understanding how nanoparticle material properties like surface chemistry, affect their transport across biological barriers including lymphatic vessels and lymph node interstitial tissues, and designing ways to use nanotechnology to study biological barriers and design therapeutics.

Seminars start at 4:00 pm, and refreshments will be served at 3:45 pm. All seminars are held in the Conference Room (1116) of the Institute for Physical Science and Technology (IPST) Building unless otherwise noted.